‘Grey’s Anatomy’ Star Eric Dane Dies at 53 After ALS Battle

Published: 20 February 2026. The English Chronicle Desk. The English Chronicle Online

Hollywood and television fans around the world are mourning the loss of actor Eric Dane, who has died at the age of 53 following a courageous battle with amyotrophic lateral sclerosis (ALS), a progressive neurological disease also known as Lou Gehrig’s disease. Dane’s family confirmed the news in a heartfelt statement, saying he passed away on Thursday afternoon surrounded by loved ones — including his devoted wife and his two daughters, Billie and Georgia.

Best known for his breakout role as Dr. Mark Sloan, affectionately nicknamed “McSteamy,” on the long-running medical drama Grey’s Anatomy, Dane became a household name and fan favourite. His performance on the ABC series from 2006 to 2012 — and later in a brief return — helped cement his place in television history. In recent years, he also garnered acclaim for his role as Cal Jacobs on HBO’s hit series Euphoria.

In April 2025, Dane publicly revealed his ALS diagnosis, shocking fans and colleagues alike. ALS is a debilitating disease that progressively attacks nerve cells in the brain and spinal cord, robbing patients of muscle control and eventually the ability to walk, speak and breathe. Following his diagnosis, Dane did not retreat from public life; rather, he used his platform to become a passionate and tireless advocate for awareness and research into the condition.

His advocacy work included speaking at a Washington news conference in June 2025 about the importance of health insurance reform for people living with ALS, and in September 2025 he was honoured as Advocate of the Year by the ALS Network — a testament to his commitment to amplifying the voices of those affected by the disease.

Dane’s final months were marked by a blend of personal struggle and professional dedication. Despite the physical toll of ALS, he continued to inspire fans and raise awareness about the disease, even as his own health declined. His planned memoir, Book of Days: A Memoir in Moments, scheduled for publication later in 2026, promises to offer a deeply personal look at his life and experiences — from his rise in Hollywood to his journey living with ALS.

Born on November 9, 1972, in California, Dane began his acting career in the early 1990s with guest roles on shows such as Saved by the Bell and Charmed, later branching into film with credits in projects including Marley & Me, Valentine’s Day and Burlesque. His television work, however, remained his most beloved contribution, particularly his portrayal of McSteamy, which earned him enduring affection from audiences worldwide.

In recent months, as ALS progressed, Dane had to adjust to the realities of his illness, at times publicly discussing the physical challenges he faced and continuing to champion research into treatments and support for others with the disease.

His family’s statement emphasised their deep love for Dane and gratitude for the support from his fans: “He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received.”

Eric Dane’s legacy extends beyond his memorable on-screen roles. His dedication to ALS awareness and the courage he demonstrated throughout his illness have already left a profound impact on both the entertainment community and the many individuals touched by his advocacy. As tributes pour in from co-stars, friends and fans alike, his influence as both an actor and a champion for ALS research will endure.

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